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Right ventricular and left ventricular function in cats with experimentally induced pulmonary hypertension.
Cardiac hemodynamics and right ventricular function were studied in 15 anesthetized cats with experimentally induced pulmonary hypertension (PEH) by infusing the systemic circulation with blood from the pulmonary circulation for 4 h via an aortic-pulmonary arterial shunt. In 12 cats, the acute reduction in right ventricular function resulted in a decrease in pulmonary artery pressure from 28 +/- 4 to 11 +/- 1 mmHg (mean +/- S.E., p less than 0.001) and a modest increase in right ventricular peak systolic pressure (from 70 +/- 5 to 80 +/- 5 mmHg, p less than 0.05). Left ventricular systolic pressure (LVS) increased from 30 +/- 3 to 39 +/- 5 mmHg (p less than 0.05) and LVS/left ventricular end-diastolic pressure (LVEDP) increased from 2.5 +/- 0.3 to 3.6 +/- 0.2 (p less than 0.001). In three cats, the increase in LVS/LVEDP was maintained after 4 h of sustained elevated pulmonary artery pressure, and in six cats, LVS/LVEDP was not elevated. Right ventricular stroke work increased in 11 cats from 29 +/- 3 to 52 +/- 6 mmHg (p less than 0.001), with a concomitant decrease in right ventricular stroke work index (RVSWI) from 4.8 +/- 0.4 to 3.7 +/- 0.5 J/kg (p less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)module AlloyTest
extend ActiveSupport::Concern
module ClassMethods
def test_override_in_rename_on_demux_ext_if_present(params)
params[:type] = 'no_ext'
params[:index] = '1'
params[:rename] = 'RenamedName'
if params[ be359ba680
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